Graduado de la Universidad de Ottawa, Facultad de Medicina en 1983,

Neurocirugía en la Universidad McGill.

Miembro del Colegio Real de Médicos y Cirujanos de Canadá en 1990.

Durante su residencia en Montreal, el Dr. Lozano obtuvo su doctorado de Medicina Experimental en 1989.

El Dr. Lozano se unió al equipo de Neurocirugía del Hospital Toronto Western en 1991.

Actualmente es profesor en el Departamento de Cirugía, y titular de la Cátedra inaugural del Presidente Ronald Tasker en neurocirugía estereotáctica y funcional de la Red de Salud de la Universidad.

También tiene un cargo en la Cátedra de Investigación en Neurociencias de Canadá.

Su investigación principal e intereses clínicos se encuentran en el campo del tratamiento neuroquirúrgico de trastornos del movimiento y registro mediante micro-electrodos en el cerebro humano.

La estimulación cerebral profunda (DBS) ha sido recientemente investigada como tratamiento para la depresión mayor.

Uno de los objetivos propuestos para esta aplicación es la circunvolución cingular subcallosa (SCG).

Publicaciones como primer autor

1: Lozano AM, Levy R. Reoperation of Deep Brain Stimulation in Patients with Essential Tremor. World Neurosurg. 2012 Jan 17. [Epub ahead of print] PubMed PMID: 22373891.

2: Lozano AM. Deep brain stimulation therapy. BMJ. 2012 Feb 21;344:e1100. doi: 10.1136/bmj.e1100. PubMed PMID: 22354581.

3: Lozano AM. The Wilson films–hemiballism. Mov Disord. 2011 Dec;26(14):2469-70. doi: 10.1002/mds.23995. PubMed PMID: 22170270.

4: Lozano AM, Giacobbe P, Hamani C, Rizvi SJ, Kennedy SH, Kolivakis TT, Debonnel G, Sadikot AF, Lam RW, Howard AK, Ilcewicz-Klimek M, Honey CR, Mayberg HS. A multicenter pilot study of subcallosal cingulate area deep brain stimulation for treatment-resistant depression. J Neurosurg. 2012 Feb;116(2):315-22. Epub 2011 Nov 18. PubMed PMID: 22098195.

5: Lozano AM. Harnessing plasticity to reset dysfunctional neurons. N Engl J Med. 2011 Apr 7;364(14):1367-8. PubMed PMID: 21470016.

6: Lozano AM. Psychosurgery. J Neurosurg. 2010 Dec;113(6):1202; discussion 1202-3. Epub 2010 Jun 18. PubMed PMID: 20560727.

7: Lozano AM, Neimat JS. Neurostimulation: from verification to exploration. Neurobiol Dis. 2010 Jun;38(3):327-8. Epub 2010 Mar 27. PubMed PMID: 20347983.

8: Lozano AM, Snyder BJ, Hamani C, Hutchison WD, Dostrovsky JO. Basal ganglia physiology and deep brain stimulation. Mov Disord. 2010;25 Suppl 1:S71-5. Review. PubMed PMID: 20187251.

9: Lozano AM, Lázaro RC, Andrés JM. [Endovascular treatment of cerebral aneurysms: review of a ten year experience]. Neurologia. 2009 Nov;24(9):797-803. Spanish. PubMed PMID: 20099152.

10: Lozano AM. Deep brain stimulation for Parkinson disease. J Neurosurg. 2010 Mar;112(3):477; discussion 477-8. PubMed PMID: 19681686.

11: Lozano AM, Snyder BJ. Deep brain stimulation for parkinsonian gait disorders. J Neurol. 2008 Aug;255 Suppl 4:30-1. Review. PubMed PMID: 18821083.

12: Lozano AM, Mayberg HS, Giacobbe P, Hamani C, Craddock RC, Kennedy SH. Subcallosal cingulate gyrus deep brain stimulation for treatment-resistant depression. Biol Psychiatry. 2008 Sep 15;64(6):461-7. Epub 2008 Jul 18. PubMed PMID: 18639234.

13: Lozano AM. Cell-based therapy for Parkinson disease. Neurosurg Focus. 2008;24(3-4):E7; discussion E7. PubMed PMID: 18341410.

14: Lozano AM, Eltahawy H. How does DBS work? Suppl Clin Neurophysiol. 2004;57:733-6. Review. PubMed PMID: 16106676.

15: Lozano AM, Kalia SK. New movement in Parkinson's. Sci Am. 2005 Jul;293(1):68-75. Erratum in: Sci Am. 2005 Nov;293(5):14. PubMed PMID: 16008304.

16: Lozano AM, Mahant N. Deep brain stimulation surgery for Parkinson's disease: mechanisms and consequences. Parkinsonism Relat Disord. 2004 May;10 Suppl 1:S49-57. Review. PubMed PMID: 15109587.

17: Lozano AM, Hamani C. The future of deep brain stimulation. J Clin Neurophysiol. 2004 Jan-Feb;21(1):68-9. PubMed PMID: 15097295.

18: Lozano AM, Abosch A. Pallidal stimulation for dystonia. Adv Neurol. 2004;94:301-8. Review. PubMed PMID: 14509687.

19: Lozano AM, Dostrovsky J, Chen R, Ashby P. Deep brain stimulation for Parkinson's disease: disrupting the disruption. Lancet Neurol. 2002 Aug;1(4):225-31. Review. PubMed PMID: 12849455.

20: Lozano AM. Surgery for Parkinson's disease, the five W's: why, who, what, where, and when. Adv Neurol. 2003;91:303-7. Review. PubMed PMID: 12442688.

21: Lozano AM, Carella F. Physiologic studies in the human brain in movement disorders. Parkinsonism Relat Disord. 2002 Sep;8(6):455-8. Review. PubMed PMID: 12217635.

22: Lozano AM, Hutchison WD. Microelectrode recordings in the pallidum. Mov Disord. 2002;17 Suppl 3:S150-4. PubMed PMID: 11948770.

23: Lozano AM, Lang AE. Pallidotomy for Parkinson's disease. Adv Neurol. 2001;86:413-20. Review. PubMed PMID: 11554004.

24: Lozano AM. Deep brain stimulation for Parkinson's disease. Parkinsonism Relat Disord. 2001 Jul;7(3):199-203. PubMed PMID: 11331187.

25: Lozano AM. The subthalamic nucleus: myth and opportunities. Mov Disord. 2001 Mar;16(2):183-4. PubMed PMID: 11295767.

26: Lozano AM. Vim thalamic stimulation for tremor. Arch Med Res. 2000 May-Jun;31(3):266-9. Review. PubMed PMID: 11036177.

27: Lozano AM, Lang AE, Levy R, Hutchison W, Dostrovsky J. Neuronal recordings in Parkinson's disease patients with dyskinesias induced by apomorphine. Ann Neurol. 2000 Apr;47(4 Suppl 1):S141-6. PubMed PMID: 10762141.

28: Lozano AM, Hutchison WD, Tasker RR, Lang AE, Junn F, Dostrovsky JO. Microelectrode recordings define the ventral posteromedial pallidotomy target. Stereotact Funct Neurosurg. 1998;71(4):153-63. PubMed PMID: 10461101.

29: Lozano AM, Lang AE, Hutchison WD, Dostrovsky JO. New developments in understanding the etiology of Parkinson's disease and in its treatment. Curr Opin Neurobiol. 1998 Dec;8(6):783-90. Review. PubMed PMID: 9914234.

30: Lozano AM, Lang AE, Hutchison WD. Pallidotomy for tremor. Mov Disord. 1998;13 Suppl 3:107-10. Review. PubMed PMID: 9827605.

31: Lozano AM, Vanderlinden G, Bachoo R, Rothbart P. Microsurgical C-2 ganglionectomy for chronic intractable occipital pain. J Neurosurg. 1998 Sep;89(3):359-65. PubMed PMID: 9724107.

32: Lozano AM, Lang AE. Pallidotomy for Parkinson's disease. Neurosurg Clin N Am. 1998 Apr;9(2):325-36. Review. PubMed PMID: 9495895.

33: Lozano AM, Kumar R, Gross RE, Giladi N, Hutchison WD, Dostrovsky JO, Lang AE. Globus pallidus internus pallidotomy for generalized dystonia. Mov Disord. 1997 Nov;12(6):865-70. PubMed PMID: 9399208.

34: Lozáno AM, Lang AE, Hutchison WD, Dostrovsky JO. Microelectrode recording-guided posteroventral pallidotomy in patients with Parkinson's disease. Adv Neurol. 1997;74:167-74. PubMed PMID: 9348412.

35: Lozano AM. Pallidotomy: Where are we? Parkinsonism Relat Disord. 1996 Apr;2(2):53-4. PubMed PMID: 18591018.

36: Lozano AM, Schmidt M, Roach A. A convenient in vitro assay for the inhibition of neurite outgrowth by adult mammalian CNS myelin using immortalized neuronal cells. J Neurosci Methods. 1995 Dec;63(1-2):23-8. PubMed PMID: 8788044.

37: Lozano AM, Lang AE, Galvez-Jimenez N, Miyasaki J, Duff J, Hutchinson WD, Dostrovsky JO. Effect of GPi pallidotomy on motor function in Parkinson's disease. Lancet. 1995 Nov 25;346(8987):1383-7. Erratum in: Lancet 1996 Oct 19;348(9034):1108. PubMed PMID: 7475819.

38: Lozano AM, Labes M, Roder J, Roach A. An antineuronal monoclonal antibody that reverses neurite growth inhibition by central nervous system myelin. J Neurosci Res. 1995 Oct 15;42(3):306-13. PubMed PMID: 8583498.

39: Lozano AM, Hutchison WD, Dostrovsky JO. Microelectrode monitoring of cortical and subcortical structures during stereotactic surgery. Acta Neurochir Suppl. 1995;64:30-4. Review. PubMed PMID: 8748579.

40: Lozano AM, Leblanc R. Cerebral aneurysms and polycystic kidney disease: a critical review. Can J Neurol Sci. 1992 May;19(2):222-7. Review. PubMed PMID: 1623450.

41: Lozano AM, Leblanc R. Familial intracranial aneurysms. J Neurosurg. 1987 Apr;66(4):522-8. PubMed PMID: 3559718.

42: Lozano AM, Mezl VA. Methylglyoxal inhibits the translation of natural and chemically decapped mRNAs. Biosci Rep. 1984 Sep;4(9):783-8. PubMed PMID: 6509161.

43: Lozano AM. Horner's syndrome following internal jugular vein catheterization. Can Med Assoc J. 1983 Sep 15;129(6):540. PubMed PMID: 6883251; PubMed Central PMCID: PMC1875551.